Current literature on the pathology of vulvar disease continues to foc
us on vulvar intraepithelial neoplasia, the role of human papillomavir
us in vulvar neoplasia, and Paget's disease of the vulva. Of particula
r concern is an increasing incidence of vulvar intraepithelial neoplas
ia noted over the past several decades, specifically among younger wom
en. Human papillomavirus has emerged as a major factor in this trend.
Furthermore, a more aggressive course may ensue in these young women,
requiring diligent follow-up.