CIRCULATION OF POLIOVIRUS AMONG RISK GROUPS IN IBADAN, NIGERIA

Authors
ADU FD ODEMUYIWA SO TOMORI O
Citation
Fd. Adu et al., CIRCULATION OF POLIOVIRUS AMONG RISK GROUPS IN IBADAN, NIGERIA, Transactions of the Royal Society of Tropical Medicine and Hygiene, 90(2), 1996, pp. 126-127
Citations number
6
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
Journal title
Transactions of the Royal Society of Tropical Medicine and Hygiene → ACNP
ISSN journal
00359203
Volume
90
Issue
2
Year of publication
1996
Pages
126 - 127
Database
ISI
SICI code
0035-9203(1996)90:2<126:COPARG>2.0.ZU;2-0
Abstract
Faecal samples collected from 114 fully vaccinated pre-school children and 32 unvaccinated infants in Ibadan, Nigeria, were assayed for poli ovirus in Hep-2 and RD cell cultures. 8 strains of poliovirus type 1 w ere isolated from 146 samples-3 from 32 unvaccinated children aged les s than 40 d and 5 from 114 fully vaccinated children aged between 9 an d 60 months. Studies using Sabin and wild monoclonal antibodies and th e polymerase chain reaction confirmed 7 of the 8 isolates to be of the wild type, a possible source of infection among vaccinated children.