LOCALIZATION OF THE HUMAN VASCULAR ENDOTHELIAL GROWTH-FACTOR GENE, VEGF AT CHROMOSOME 6P12

Using overlapping cosmids representing the vascular endothelial growth factor (VEGF) locus, the VEGF gene was mapped by fluorescence in situ hybridization to chromosome 6p12. This localization permits linkage a nalysis and the identification of gene interaction in the region, as w ell as alterations of the VEGF structure or expression in cancer cells with chromosome abnormalities.