OCULAR LYMPHOBLASTIC CRISIS IN CHRONIC MYELOGENOUS LEUKEMIA

A patient who was known to have chronic myeloid leukemia (CML) in tota l systemic remission presented with bilateral pseudohypopyon and exuda tive retinal detachment. Anterior chamber fluid cytology revealed nume rous lymphoblasts. Because peripheral blood and bone marrow profiles w ere normal, a diagnosis of localized lymphoblastic crisis was establis hed. The possibility of lymphoblastic transformation in a uveal extram edullary hematopoietic focus is confronted by the theory of lymphoblas tic transformation of uveal leukemic infiltrates that serve as a tumor rest untouched by the original chemotherapy.