SYNTHESIS AND HPLC-SEPARATION OF ATROPISO MERIC AND CENTRAL CHIRAL 3-ARYL-2-MERCAPTO-4(3H)-QUINAZOLINONE AND 3-ARYL-2-ALKYLTHIO-4(3H)-QUINAZOLINONE DERIVATIVES ON CHIRAL STATIONARY PHASES .1. SYNTHESIS

Authors
JIRA T JUNGHANEL J THEISS R KOTTKE K BESCH A SCHOPPLICH C BUNKE A LEUTHOLD J BEYRICH T
Citation
T. Jira et al., SYNTHESIS AND HPLC-SEPARATION OF ATROPISO MERIC AND CENTRAL CHIRAL 3-ARYL-2-MERCAPTO-4(3H)-QUINAZOLINONE AND 3-ARYL-2-ALKYLTHIO-4(3H)-QUINAZOLINONE DERIVATIVES ON CHIRAL STATIONARY PHASES .1. SYNTHESIS, Die Pharmazie, 51(5), 1996, pp. 273-279
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
51
Issue
5
Year of publication
1996
Pages
273 - 279
Database
ISI
SICI code
0031-7144(1996)51:5<273:SAHOAM>2.0.ZU;2-T
Abstract
In this paper the synthesis of atropisomeric and central chiral 3-aryl -2-mercapto-, 3-aryl-2-alkylthio-4 (3H)-quinazolinones with a chiral s ide chain are described. The spectroscopical data of the analytes and the HPLC-parameters on RP-phases are presented.