To assess the value of sacral neuromodulation for treatment of neuroge
nic bladder dysfunction, 27 patients (19 women, 8 men; mean age 44.9 y
ears) underwent acute and subchronic testing before chronic electrode
implantation on a dorsal 53 foramen. Fifteen patients had urgency/freq
uency owing to detrusor hyperreflexia and/or bladder hypersensitivity,
11 had urinary retention owing to detrusor areflexia, and 1 had combi
ned bladder hypersensitivity and detrusor areflexia. Twelve patients (
11 women and 1 man) underwent chronic neurostimulation. Mean follow-up
evaluation, by voiding diary and repeated urodynamics, was 17 months
(4-35 months). Severe side effects were encountered in 2 patients in w
hom the implant had to be removed (1 with infection, 1 with adverse se
nsation during stimulation), minor and tolerable side effects in anoth
er 3 patients. In 8 patients the urologic sequelae of the neurologic d
isorder were alleviated significantly (50% or more), in 5 of them chro
nic neuromodulation was as effective as preoperative testing. Chronic
sacral neuromodulation can be valuable for treating neurogenic bladder
dysfunction. However, preoperative evaluation and surgical techniques
must be further refined to achieve long-term results that are at leas
t as effective as those of preoperative testing.