Jr. Sutcliffe et al., ANTENATAL TESTICULAR TORSION - ONLY ONE CAUSE OF THE TESTICULAR REGRESSION SYNDROME, Journal of the Royal College of Surgeons of Edinburgh, 41(2), 1996, pp. 99-101
It has been suggested that the most likely cause of the Testicular Reg
ression Syndrome (TRS) is antenatal torsion of the testis. As testicul
ar torsion is twice as common on the left this theory cannot explain t
he incidence of right sided or bilateral cases. From a 5-year retrospe
ctive surgical and pathological review, we confirmed that the left tes
tis was the most commonly affected, that boys with TRS tended to be de
livered closer to term, and that frequently both testes were present a
t birth, but one or both subsequently vanished. We also found that dir
ect trauma can produce histological findings indistinguishable from TR
S. Close to term, fetal testes are liable to be intrascrotal and there
fore susceptible to direct trauma. As the left testis descends into th
e scrotum at an earlier stage than the right, it is therefore at great
er risk of injury. Since the findings of TRS can be produced by direct
trauma, we suggest that intra-partum trauma may predispose to the TRS
.