E. Truve et al., THE EFFECTS OF 2-5A ON PROTEIN-SYNTHESIS IN WHEAT-GERM EXTRACTS AND TOBACCO PROTOPLASTS, Nucleosides & nucleotides, 15(5), 1996, pp. 1097-1111
Nonphosphorylated 2-5A inhibited translation and caused RNA degradatio
n in wheat germ extract, whereas 3-5A had no effect. Protein synthesis
inhibition by 2-5A was observed in tobacco protoplasts. 70 kD 2-5A-bi
nding protein was found in potato leaf extracts by chemical crosslinki
ng.