G. Elhajj et G. Anneroth, ODONTOGENIC KERATOCYSTS - A RETROSPECTIVE CLINICAL AND HISTOLOGIC-STUDY, International journal of oral and maxillofacial surgery, 25(2), 1996, pp. 124-129
Including 25 recurrences, the material comprised 87 odontogenic kerato
cysts (OKCs) from 57 patients, who had been treated in 1974-93. The st
udy included an analysis of clinical and histologic data from the pati
ents' records and from pathologic reports. The men:women ratio was 1.5
:1. Most of the patients belonged to the age groups 10-19, 20-29, 40-4
9, and 60-69 years. Almost 75% of the OKCs were localized in the mandi
ble. The most common site was the angle and ascending ramus area. Recu
rrences comprised 30.5% of the OKCs. The symphysial area of the mandib
le had the highest recurrence rate (50%). The diagnosis of Gorlin's sy
ndrome was established in two patients. The recurrence rates for the O
KCs that were removed in one or in several pieces were 27.5% and 39%,
respectively. In 14/87 (16%) cases, microkeratocysts were histological
ly found. Parakeratosis was observed in 78/87 (89.5%), ortho- and para
keratosis in 6/87 (7%), and orthokeratosis in 3/87 (3.5%) cases. The r
ecurrence rates were 31.5% and 41% for the OKCs that were removed duri
ng 1974, 1984, and 1985-90, respectively. In no case could malignant c
hanges be observed at histologic examination.