ANALYSIS OF BLOOD IMMUNOGENETIC MARKERS A SSOCIATIONS WITH LYMPHOGRANULOMATOSIS IN ARMENIAN COMMUNITY

Authors
NERSISYAN VM MUSAELYAN NO MARTIROSYAN IG
Citation
Vm. Nersisyan et al., ANALYSIS OF BLOOD IMMUNOGENETIC MARKERS A SSOCIATIONS WITH LYMPHOGRANULOMATOSIS IN ARMENIAN COMMUNITY, Gematologia i transfuziologia, 40(6), 1995, pp. 7-10
Citations number
14
Categorie Soggetti
Hematology
Journal title
Gematologia i transfuziologia → ACNP
ISSN journal
02345730
Volume
40
Issue
6
Year of publication
1995
Pages
7 - 10
Database
ISI
SICI code
0234-5730(1995)40:6<7:AOBIMA>2.0.ZU;2-X
Abstract
A study of 11 immunogenetical blood systems (HLA-A, B, C, DR; ABO; Rh- Hr; MNSs; Kidd; Kell-Chellano; Duffy; Lewis; Diego; Gm; Inv) involving 59 antigens was performed in patients of Armenian nationality with ly mphogranulomatosis (LGM). Pathogenic associations of HLA, MNSs and Duf fy systems with LGM were established. Positive correlations were found (p<0.001) with HLA phenotypes DR-8, B-14, B-21, SS, Fy(a+b-). These p henotypes have significant correlation with LGM (RR=4.7-2.1) and can b e considered as genetic markers of LGM in the Armenian population.