BIOCATALYSIS IN ORGANIC-SYNTHESIS .7. ENANTIOSELECTIVE TRANSESTERIFICATIONS CATALYZED BY AN ACYLASE - REMARKABLE INFLUENCE OF REMOTE SUBSTITUTION AND THE NATURE OF THE SOLVENT ON THE SELECTIVITY

Authors
ORS M MORCUENDE A JIMENEZVACAS MI VALVERDE S HERRADON B
Citation
M. Ors et al., BIOCATALYSIS IN ORGANIC-SYNTHESIS .7. ENANTIOSELECTIVE TRANSESTERIFICATIONS CATALYZED BY AN ACYLASE - REMARKABLE INFLUENCE OF REMOTE SUBSTITUTION AND THE NATURE OF THE SOLVENT ON THE SELECTIVITY, Synlett, (5), 1996, pp. 449
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1996
Database
ISI
SICI code
0936-5214(1996):5<449:BIO.ET>2.0.ZU;2-H
Abstract
Acylase I from Aspergillus species catalyzes the reaction of transeste rification between vinyl acetate and racemic derivatives of 2-(hydroxy methyl)piperidine. It has been found that the enantioselectivity of th e reaction depends on the solvent. Also it has been observed that remo te substituents have a great influence on the enantioselectivity.