L. Ambrosio et al., COMPOSITE HYDROGELS FOR INTERVERTEBRAL DISC PROSTHESES, Journal of materials science. Materials in medicine, 7(5), 1996, pp. 251-254
Different PHEMA/PCL semi-IPNs hydrogels and their relative composite s
ystems reinforced with PET fibres have been investigated for potential
use as intervertebral disc prostheses. Compression properties and wat
er absorption were evaluated. Uniaxial compression tests on the swolle
n samples showed an increase of the modulus and maximum stress with in
creasing content of PCL and PET fibres. In particular, the composite P
HEMA/PCL hydrogels showed compression properties similar to those expr
essed by the canine intervertebral discs in different spinal locations
. The equilibrium water content of modified semi-IPNs decreased as fun
ction of the PCL and PET fibres. These tests indicate that the use of
composite hydrogels as disc prostheses is very promising because it is
possible to combine transport and mechanical properties which are cru
cial for the performance of the intervertebral disc.