Aa. Safa et al., DETECTION AND TREATMENT OF DYSFUNCTIONAL HEMODIALYSIS ACCESS GRAFTS -EFFECT OF A SURVEILLANCE PROGRAM ON GRAFT PATENCY AND THE INCIDENCE OF THROMBOSIS, Radiology, 199(3), 1996, pp. 653-657
PURPOSE: To determine the value of a hemodialysis graft surveillance p
rogram in reducing the incidence of graft thrombosis and prolonging gr
aft patency by means of early detection and percutaneous transluminal
angioplasty (PTA) of graft-related stenoses. MATERIALS AND METHODS: Fo
r 41/2 years, routine graft examination and measurement of several dia
lysis parameters were used to identify 106 cases of suspected graft dy
sfunction in 57 patients (56 men, one woman; aged 27-76 years). Graft-
related stenoses detected with angiography were treated with PTA. RESU
LTS: Abnormal physical examination findings were the most com mon sole
indication of graft dysfunction. Of the 106 cases referred for angiog
raphic evaluation, 97 (92%) had at least one lesion. PTA was successfu
l in 88 of 90 treated cases. The primary patency rates at 1 year were
16% for arteriovenous fistulas (AVFs) and 23% for polytetrafluoroethyl
ene (PTFE) grafts. Early detection of stenoses by means of surveillanc
e and repeated PTA enabled 1-year primary assisted patency rates of 67
% for AVFs and 68% for PTFE grafts. The incidence of graft thrombosis
fell from 48% in 1988 to 17% in 1994 (P < .001). CONCLUSION: The hemod
ialysis graft surveillance program resulted in a statistically signifi
cant reduction in the incidence of graft thrombosis. Although primary
patency rates after PTA were low, repeated PTA of detected stenoses al
lowed good primary assisted patency rates.