PURPOSE: To determine the clinical, radiologic, and pathologic finding
s of inverted Meckel diverticulum by retrospectively reviewing a large
series of cases. MATERIALS AND METHODS: Among 84 cases of Meckel dive
rticulum, 18 (21%) were found at surgery to be inverted into the lumen
of the bowel. Thirteen of these 18 (72%) cases were associated with s
mall bowel intussusception and five (28%) were not. RESULTS: All 18 pa
tients (median age at time of diagnosis, 32 years) were symptomatic, b
ut the symptoms were subacute or chronic in 14 (78%). At barium examin
ation in 15 cases, inverted diverticulum was depicted in 10 (67%) as a
solitary, elongated, smoothly marginated, often club-shaped intralumi
nal mass in the distal. ileum. At computed tomography (CT) in three ca
ses, a central area of fat attenuation was surrounded by a thick colla
r of soft-tissue attenuation. At ultrasound (US) in two cases, a targe
tlike mass contained a central area of increased echogenicity. At path
ologic examination in all cases, the inverted sac contained mesenteric
fat. CONCLUSION: Inverted Meckel diverticulum occurs more commonly th
an previously recognized and is associated with characteristic finding
s at barium examination, CT, and US.