L. Franchini et al., FLUVOXAMINE AND LITHIUM IN LONG-TERM TREATMENT OF UNIPOLAR SUBJECTS WITH HIGH RECURRENCE RATE, Journal of affective disorders, 38(1), 1996, pp. 67-69
We prolonged from 24 to 36 months a follow-up study of unipolar subjec
ts with a high probability of recurrence treated with fluvoxamine (n =
32) or lithium (n = 32). During the extra observation period, two pat
ients developed mania and were excluded from the study. There were no
further recurrences in either the lithium or the fluvoxamine group. In
our sample, previous prescriptions of tricyclics seem to predict a wo
rse prognosis.