Study Design. The authors sought to measure the stiffness at the lumbo
sacral junction when it has been immobilized by means of two different
posterior fixation systems in conjunction with three different anteri
or interbody fixation techniques. The information obtained provides a
foundation for determining how methods of lumbosacral spinal fixation
can maximize rigidity and improve fusion rates at this clinically impo
rtant anatomic site. Objectives. To determine which spinal instrumenta
tion systems, alone or in combination, provide the most stability at t
he lumbosacral junction. Summary of Background Data. In the clinical s
etting, several different posterior instrumentation systems are curren
tly used, but the stability of these systems, when used in conjunction
with anterior interbody fixation, has not been adequately tested. The
authors hypothesized that rigidity of fixation at the lumbosacral jun
ction may be enhanced by use of appropriate anterior interbody fixatio
n techniques. Methods. Two posterior and three anterior fusion constru
cts were tested in eight fresh-frozen human cadaveric specimens in axi
al compression and torsion, flexion, extension, and lateral bending. R
esults. The isolated posterior instrumentation constructs produced gre
ater intervertebral stiffness than the isolated anterior constructs te
sted. The Jackson instrumentation was stiffer than the Galveston in ax
ial torsion and flexion. Anteriorly, the femoral ring was stiffer than
either the threaded interbody fusion device in flexion or the cortico
cancellous bone graft in flexion and compression. The threaded interbo
dy fusion device was the stiffest anterior construct in axial torsion.
Conclusions. The authors' data demonstrate that the threaded interbod
y fusion device may be an effective system for immobilization of the L
5-S1 disc space. Rigidity of fixation at the lumbosacral junction may
be enhanced by use of appropriate anterior interbody fusion techniques
.