CONTRIBUTION OF TYPE-1 PILI IN THE PATHOGENESIS OF EXPERIMENTAL MURINE CHRONIC PYELONEPHRITIS IN RELATION TO BIOCHEMICAL PARAMETERS

Authors
GUPTA R GANGULI NK
Citation
R. Gupta et Nk. Ganguli, CONTRIBUTION OF TYPE-1 PILI IN THE PATHOGENESIS OF EXPERIMENTAL MURINE CHRONIC PYELONEPHRITIS IN RELATION TO BIOCHEMICAL PARAMETERS, Medical microbiology letters, 5(3), 1996, pp. 105-112
Citations number
13
Categorie Soggetti
Microbiology
Journal title
Medical microbiology letters → ACNP
ISSN journal
10184627
Volume
5
Issue
3
Year of publication
1996
Pages
105 - 112
Database
ISI
SICI code
1018-4627(1996)5:3<105:COTPIT>2.0.ZU;2-Q
Abstract
Two standard strains of uropathogenic Escherichia coli, i.e., E. coli 31-B (MS+) and E. coli BH-5 (a mutant MS(-)), were employed to assess the mechanism of renal tissue injury in an ascending non-obstructive m ouse model for chronic pyelonephritis. We found that strain BH-5 (MS(- )) was able to bring about more biochemical alterations leading to gen eration of more reactive oxygen species and to renal scarring.