A NEW BETA-CARBOLINE ALKALOID ISOLATED FROM THE MARINE SPONGE HYRTIOS-ERECTA

Authors
BOURGUETKONDRACKI ML MARTIN MT GUYOT M
Citation
Ml. Bourguetkondracki et al., A NEW BETA-CARBOLINE ALKALOID ISOLATED FROM THE MARINE SPONGE HYRTIOS-ERECTA, Tetrahedron letters, 37(20), 1996, pp. 3457-3460
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
20
Year of publication
1996
Pages
3457 - 3460
Database
ISI
SICI code
0040-4039(1996)37:20<3457:ANBAIF>2.0.ZU;2-Y
Abstract
A novel beta-carboline alkaloid, called hyrtiomanzamine, was isolated from the marine sponge Hyrtios erecta collected in the Red Sea Its str ucture elucidation was carried out by application of various one and t wo D NMR methods. Hyrtiomanzamine 1 is the first 6-OH-beta-carboline r ing associated to a betaine unit isolated from the marine sponge Hyrti os erecta. Hyrtiomanzamine 1 showed immunosuppressive activity in the B lymphocytes reaction assay. Copyright (C) 1996 Elsevier Science Ltd