QUALITY-OF-LIFE IN GASTRIC-CANCER PRIOR TO GASTRECTOMY

A growing number of surgical trials include quality of life variables in the overall assessment of outcomes. This is believed to broaden the criteria for choice of treatment and the evaluation of treatment regi mens. The present study is a baseline evaluation of the health-related quality of life in patients with gastric cancer facing surgery. The q uality of life in these patients was related to that of other patient groups referred for surgical interventions and general population grou ps. Our study included 103 consecutive patients with carcinoma of the stomach considered amenable to a curative major surgical procedure. Th e quality of life evaluation was based on a battery of questionnaires, covering general body symptoms, mood level and functional limitations . Patients with gastric cancer reported more neurasthenic complaints s uch as reduced sexual interest, insomnia and poor appetite as well as a lower mood level than the general population. The gastric cancer gro up also showed a markedly lower mood level in comparison with a group of cancer survivors 2-3 years after diagnosis and patients with interm ittent claudication. The mental well-being of gastric cancer patients matched that of cancer survivors with one or more recurrences. Overall , 25% of the gastric cancer patients reported functional limitations r egarded as clinically significant. Patients with intermittent claudica tion reported more and patients with small cell lung cancer markedly m ore limitations. We conclude that although patients with gastric cance r showed a low level of limitations on average, problems in the areas of sleep/rest, home management and, especially, eating were frequently reported.