A method was developed for performing T1-weighted magnetic resonance i
maging with the rapid acquisition with relaxation enhancement (RARE) s
equence by altering the excitation flip angle, This method was called
variable flip angle turbo spin-echo (VF-TSF) imaging, When the effecti
ve echo time corresponds to the first echo, the resolution worsens as
the echo train length becomes longer, For this reason, the echo train
length was set at three, the repetition time (TR) was shortened (100-2
00 msec) to decrease imaging time, and the initial flip angle was adju
sted (120 degrees-140 degrees) to improve image quality, Another advan
tage of this method is that the initial flip angle can be reduced to b
elow 90 degrees when a longer TR is needed, Measured signal intensitie
s for VF-TSE imaging matched theoretic predictions, VF-TSE imaging yie
lded high contrast-to-noise and signal-to-noise ratios without sacrifi
cing resolution, The VF-TSE technique was useful for breath-hold, thre
e-dimensional, and cardiac synchronization imaging.