RELAXATION OF PBR322 FORM-I DNA BY COPPER(II) COMPLEX AND HYDROGEN-PEROXIDE

Authors
KOBAYASHI T ITO S HAMAZAKI H OHBA S NISHIDA Y
Citation
T. Kobayashi et al., RELAXATION OF PBR322 FORM-I DNA BY COPPER(II) COMPLEX AND HYDROGEN-PEROXIDE, Chemistry Letters, (5), 1996, pp. 347-348
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
5
Year of publication
1996
Pages
347 - 348
Database
ISI
SICI code
0366-7022(1996):5<347:ROPFDB>2.0.ZU;2-2
Abstract
Relaxation of pBR322 form I DNA by copper(II) complex and hydrogen per oxide systems was found to be highly dependent on the chelate structur e of copper(II) complex used. This is suggesting that an active specie s for nicking DNA may be a copper(II)hydroperoxide adduct.