CHIRAL LIGANDS DERIVED FROM ABRINE .2. OXAZOLIDINES AS PROMOTERS FOR ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TOWARD AROMATIC-ALDEHYDES

Authors
DAI WM ZHU HJ HAO XJ
Citation
Wm. Dai et al., CHIRAL LIGANDS DERIVED FROM ABRINE .2. OXAZOLIDINES AS PROMOTERS FOR ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TOWARD AROMATIC-ALDEHYDES, Tetrahedron : asymmetry, 7(5), 1996, pp. 1245-1248
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
5
Year of publication
1996
Pages
1245 - 1248
Database
ISI
SICI code
0957-4166(1996)7:5<1245:CLDFA.>2.0.ZU;2-E
Abstract
A number of indole-containing chiral oxazolidines 2a-i have been synth esized from Abrine readily available from the seeds of Abrus precatori us. Catalysis of these oxazolidines for the addition of diethylzinc to ward benzaldehyde was examined. A significant role of the substituent( s) in the catalyst on the degree of asymmetric induction was noted. Mo derate enantioselectivity up to 59.8% was recorded. Copyright (C) 1996 Published by Elsevier Science Ltd