DIASTEREOSELECTIVE SYNTHESIS OF (1S,2S,3R,4R) AND 3R,4S)-BICYCLO[2.2.1]HEPT-2-AMINO-2,3-DICARBOXYLIC ACIDS - NEW CONFORMATIONALLY-CONSTRAINED (S)-ASPARTIC ACID ANALOGS
E. Bunuel et al., DIASTEREOSELECTIVE SYNTHESIS OF (1S,2S,3R,4R) AND 3R,4S)-BICYCLO[2.2.1]HEPT-2-AMINO-2,3-DICARBOXYLIC ACIDS - NEW CONFORMATIONALLY-CONSTRAINED (S)-ASPARTIC ACID ANALOGS, Tetrahedron : asymmetry, 7(5), 1996, pp. 1521-1528
The title compounds were prepared from key intermediates readily obtai
ned by the stereoselective Diels-Alder reaction of ethyl-1,3-dioxolan-
4-ylmethylene]-5(4H)-oxazolone, a chiral az-lactone derived from (R)-g
lyceraldehyde and cyclopentadiene. Copyright (C) 1996 Elsevier Science
Ltd