S. Bopp et al., RETINAL LESIONS EXPERIMENTALLY PRODUCED BY INTRAVITREAL ULTRASOUND, Graefe's archive for clinical and experimental ophthalmology, 231(5), 1993, pp. 295-302
Currently, vitreous surgical techniques combined with phacoemulsificat
ion are an established procedure for the removal of luxated natural le
nses or dislocated lenticular material. This has proven to be a safe p
rocedure, but occasionally retinal lesions have been inadvertently cre
ated. We describe the ophthalmoscopic and morphologic features of ultr
asonically induced retinal lesions in rabbit eyes using a similar tech
nique. The retina was treated directly using a conventional ultrasound
tip for pars plana lensectomy (Fragmatome). Ophthalmoscopically sligh
t lesions corresponded to an area of retinal whitening. More severe le
sions showed a destruction of the inner retina and created a retinal b
reak. Extensive effects also involved the choroid and led to a retinal
defect with rupture of choroidal vessels and heavy bleeding into the
vitreous cavity. Histologic evaluation showed that the acoustic energy
primarily led to damage of the outer retina, latter involving the inn
er retina and the choroid as well.