This paper reviews some illustrative examples of studies of human neur
obehavioral effects from experimental as well as long-term occupationa
l organic-solvent exposure. My objective is to present a selection of
neurobehavioral solvent studies with the educational aim that we may h
opefully learn from the early experiences of others. Some of the metho
dological problems encountered in these studies are discussed, as well
as some reasons for the relative success of the work performed by cer
tain Scandinavian research teams.