EFFECTIVENESS OF NEDOCROMIL SODIUM IN PREVENTING EXERCISE-INDUCED ASTHMA IN CHILDREN

Exercise-induced asthma is a well-known phenomenon, particularly affec ting children, with an important social impact, Ln order to assess the usefulness of nedocromil sodium in the prevention of exercise-induced asthma, we studied 49 (15 females, 34 males) children who suffered fr om asthma; their mean+/-SD age was 9.2+/-3.0 (range: 3.3-19.1) gears. On the first day respiratory function was evaluated bg spirometry, bas ally and after 6 minutes, The inhalation of nedocromil sodium had a gr eat influence on post-exercise lung function measurements; in fact on the day of nedocromil sodium pretreatment, our patients showed an incr ease of respiratory function, significantly different from the paramet ers recorded during the first day, Our findings suggest that nedocromi l sodium is effective in the prevention of exercise-induced asthma, in pediatric age.