GANGLIOSIDE LONG-CHAIN BASE COMPOSITION OF RAT-BRAIN SUBCELLULAR-FRACTIONS AFTER CHRONIC ETHANOL ADMINISTRATION

Authors
OMODEOSALE F GORNATI R PALESTINI P
Citation
F. Omodeosale et al., GANGLIOSIDE LONG-CHAIN BASE COMPOSITION OF RAT-BRAIN SUBCELLULAR-FRACTIONS AFTER CHRONIC ETHANOL ADMINISTRATION, Alcohol, 13(3), 1996, pp. 291-295
Citations number
41
Categorie Soggetti
Substance Abuse","Pharmacology & Pharmacy",Toxicology
Journal title
Alcohol → ACNP
ISSN journal
07418329
Volume
13
Issue
3
Year of publication
1996
Pages
291 - 295
Database
ISI
SICI code
0741-8329(1996)13:3<291:GLBCOR>2.0.ZU;2-3
Abstract
Rats of two different ages (2 and 7 months) were treated with an ethan ol-containing liquid diet for 24 days and changes of the ceramide comp osition of gangliosides were studied in the brain synaptosomal, micros omal and myelin fractions. Greater differences were observed in the yo unger age, where ethanol treatment caused a significant increase of C2 0 : 1 LCB in GM1 ganglioside of synaptosomes and microsomes and in GD1 a of myelin.