Congenital aplasia of the iris sphincter and dilator muscles is rare.
We describe a 3-month-old boy with a patent ductus arteriosus who had
this anomaly, with no other ocular or systemic abnormalities. The chil
d, whom we followed for over 7 years, had reduced accommodative amplit
udes. This anomaly, although it bears some similarity to Gillespie's s
yndrome, circumpupillary aplasia and aniridia, is an isolated, nonprog
ressive condition that general physicians need to differentiate from t
he neurologically dilated pupil so that misdirected, unnecessary inves
tigations can be avoided.