INHIBITORY EFFECTS OF SCOPADULCIC ACID-B AND ITS DERIVATIVES ON BONE-RESORPTION AND OSTEOCLAST FORMATION IN-VITRO

Authors
MIYAHARA T HAYASHI T MATSUDA S YAMADA R IKEDA K TONOYAMA H KOMIYAMA H MATSUMOTO M NEMOTO N SANKAWA U
Citation
T. Miyahara et al., INHIBITORY EFFECTS OF SCOPADULCIC ACID-B AND ITS DERIVATIVES ON BONE-RESORPTION AND OSTEOCLAST FORMATION IN-VITRO, Bioorganic & medicinal chemistry letters, 6(9), 1996, pp. 1037-1042
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
9
Year of publication
1996
Pages
1037 - 1042
Database
ISI
SICI code
0960-894X(1996)6:9<1037:IEOSAA>2.0.ZU;2-U
Abstract
Scopadulcic acid B and its structurally related compounds showed inhib itory effects on bone resorption and osteoclast formation in vitro. Sc opadulciol was the most potent inhibitor among 21 compounds tested. (C ) 1996 Elsevier Science Ltd.