Primary sarcomas of the lung are extremely rare. Among the most common
to occur in this location ore leiomyosarcoma, fibrosarcoma, and heman
giopericytoma. Many difficulties are encountered when establishing the
se sarcoma diagnoses, or one of another pathologic type, because of ov
erlapping histologic features and morphologic similarities between pri
mary and metastatic lesions. In this study, the diagnosis of a primary
monophasic synovial sarcoma of the lung was aided by the observation
of the X;18 translocation characteristic of this neoplasm. To the best
of our knowledge, this is the first cytogenetic report of a primary p
ulmonary synovial sarcoma.