The association between the Angle classification and craniofacial form
has been analysed with the aid of multiple linear regression analysis
in a sample of 170 children, before orthodontic treatment had started
. It was found that part of the differences between Class II, Class I,
and Class III was accounted for by systematical variation in a cohere
nt set of midface and cranial base dimensions. These variations were i
n harmony with each other: the cranial base angle Ba-S-N closed and th
e legs S-N and S-Ba shortened systematically from Class II, over Class
I, to Class III. The juvenile mandible notably was not systematically
different. Because the cranial base provides the framework for the ma
xilla to be built upon, it is concluded that in juveniles the midface
above anything else creates the characteristic difference between the
three Angle classes, not the mandible. The Angle classification of mal
occlusion, therefore, represents three arbitrary markers on a morpholo
gical continuum.