Purpose: To determine the incidence, duration, and risk factors for ci
liochoroidal effusion after panretinal photocoagulation. Methods: Thir
ty-nine consecutive patients with diabetic retinopathy underwent ultra
sound biomicroscopy of both eyes to image the ciliochoroidal space imm
ediately before and 1 day after unilateral argon-green panretinal phot
ocoagulation. Imaging was repeated on days 3, 7, and 14 in patients in
whom ciliochoroidal effusion developed. Results: Low-lying ciliochoro
idal effusions were imaged in 23 (59%) of 39 eyes. Of 23 eyes, effusio
ns resolved in 6 (26%), 12 (52%), and 5 (22%) eyes by 3, 7, and 14 day
s, respectively, The number of laser applications (P = 0.02), shorter
axial length (P = 0.01), and percentage of retinal surface area treate
d (P = 0.02) were associated with the development of effusion. Age, se
x, eye, type and duration of diabetes, presence of systemic hypertensi
on, location of treatment, previous panretinal photocoagulation or cat
aract surgery, retinal surface area treated, and mean blood pressure b
efore photocoagulation were not associated with effusion. All fellow,
untreated eyes remained effusion-free. Conclusion: Ciliochoroidal effu
sion develops commonly after panretinal photocoagulation. Limiting the
number of laser applications and the percentage of retinal surface ar
ea treated reduces the likelihood of this complication. Eyes with shor
ter axial lengths are at higher risk.