INFECTION OF PIGS BY AEROSOLS OF AUJESZKYS-DISEASE VIRUS AND THEIR SHEDDING OF THE VIRUS

On three consecutive days, six pigs were exposed for 15 minutes to aer osols of Aujeszky's disease virus. The total estimated dose was 45 log (10) TCID50. Within each isolation room. a sentinel pig was placed on a deck two feet away from the infected pig. The breath of the pigs tha t had inhaled the aerosols was collected on days 3, 7 and 13. The resp iratory and other clinical signs of the infected pigs resembled those in field cases of Aujeszky's disease. All the pigs infected with Aujes zky's disease virus seroconverted within seven to 10 days after infect ion. Among the sentinel pigs, clinical signs were minimal and only thr ee seroconverted.