Lactic acid was produced by immobilized Lactobacillus delbreuckii cell
s in a fixed-bed reactor and then separated by a column packed with po
ly(4-vinylpyridine) as an adsorbent. Satisfactory simulation results w
ere obtained by describing the fermentation process using a fermentati
on kinetics model with axial dispersion and the column adsorption proc
ess using a linear-driving-force model.