ASSESSMENT OF OVARIAN SENSITIVITY TO GONA DOTROPINS BY OVARIAN RESERVE TESTS

Among several parameters involved in the age-dependant reduction in co nception rate, infra-ovarian factors, specially the follicular oocyte complex, play a major role. The aim of endocrine challenge tests is to assess ovarian follicular reserve. Basal serum FSH determination on d ay 3 of the cycle is easily measurable, inexpensive, Ifs sensitivity i s increased with a clomiphene citrate challenge test, Both GnRH agonis t stimulation test and exogenous FSH test allow to evaluate more direc tly the ovarian function. However they are more invasive, expensive an d need further standardisation.