B. Laubscher et al., HEMODYNAMIC-CHANGES DURING HIGH-FREQUENCY OSCILLATION FOR RESPIRATORY-DISTRESS SYNDROME, Archives of Disease in Childhood, 74(3), 1996, pp. 172-176
In a crossover trial left ventricular output (LVO), cerebral blood flo
w velocity (CBFV), and resistance index (RI) of the anterior cerebral
artery were compared using Doppler ultrasonography, in eight preterm i
nfants with respiratory distress syndrome (RDS) during conventional me
chanical ventilation and high frequency oscillation. LVO was 14% to 18
% lower with high frequency oscillation. There were no significant cha
nges in CBFV. On the first day of life there was a trend towards lower
RI on high frequency oscillation; the fall in LVO on high frequency o
scillation was not related to lung hyperinflation. Changes in ventilat
ion type (from conventional mechanical ventilation to high frequency o
scillation, or vice versa) can induce significant LVO changes in prete
rm infants with RDS.