Authors
Citation
Je. Peake et al., X-LINKED IMMUNE DYSREGULATION, NEONATAL INSULIN-DEPENDENT DIABETES, AND INTRACTABLE DIARRHEA, Archives of Disease in Childhood, 74(3), 1996, pp. 195-199
Citations number
21
Categorie Soggetti
Pediatrics
Journal title
ISSN journal
00039888
Volume
74
Issue
3
Year of publication
1996
Pages
195 - 199
Database
ISI
SICI code
0003-9888(1996)74:3<195:XIDNID>2.0.ZU;2-H
Abstract
Four related male infants presented with neonatal diabetes mellitus, i
mmune dysregulation with extremely high concentrations of immunoglobul
in E, and intractable diarrhoea. They were all hem one family, and all
of them died. As far as is known this X-linked recessive disorder has
not been described before. It is suggested that this is a new immunod
eficiency in which type 2 T helper responses predominate.