A PHASE-II TRIAL OF FLUDARABINE IN PATIENTS WITH PREVIOUSLY TREATED CHRONIC LYMPHOCYTIC-LEUKEMIA

Authors
HOCEPIED AMLJ FALKSON CI FALKSON G
Citation
Amlj. Hocepied et al., A PHASE-II TRIAL OF FLUDARABINE IN PATIENTS WITH PREVIOUSLY TREATED CHRONIC LYMPHOCYTIC-LEUKEMIA, South African medical journal, 86(5), 1996, pp. 549-550
Citations number
4
Categorie Soggetti
Medicine, General & Internal
Journal title
South African medical journal → ACNP
ISSN journal
02569574
Volume
86
Issue
5
Year of publication
1996
Pages
549 - 550
Database
ISI
SICI code
0256-9574(1996)86:5<549:APTOFI>2.0.ZU;2-0
Abstract
Objectives. To evaluate fludarabine in patients with chronic lymphocyt ic leukaemia (CLL) not responding to standard treatment. Design settin g. Fludarabine was administered for 5 consecutive days and repeated 4- weekly. Subjects. Seventeen patients at a single institution were trea ted. Outcome measures. Objective remission was seen in 11 patients, Th e median survival time was 356 days. Results and conclusions. fludarab ine is an effective treatment for patients with advanced CLL.