Granulomatous slack skin disease (GSS) is a rare disorder characterize
d by bulky cutaneous lesions and epithelioid and giant cell granulomas
with destruction of the dermal elastic tissue. We detail the observat
ion of a 29-year-old man with clinical and histological features of GS
S. Pendulous skin tumors were associated with typical clinical and imm
unohistochemical aspects of mycosis fungoides and with clonal rearrang
ement of the V gamma T-cell receptor gene in lesional skin. This case
report supports cutaneous T-cell lymphoma as a cause of GSS.