THE EFFECTS OF VERAPAMIL AND LIDOCAINE ON THE DURATION OF PROPOFOL AND XYLAZINE-KETAMINE ANESTHESIA IN BROILER-CHICKENS

The effects of verapamil, a calcium channel blocker, and lidocaine, a sodium channel blocker, administration on the duration of 1 mg propofo l/kg iv or 5 mg xylazine/kg + 15 mg ketamine/kg im anesthesia were exa mined in and 6-w-old broiler chickens. The use of 2.5 or 1.25 mg verap amil/kg Im or 5 mg 1 idocaine/kg Im prolonged the sleep time induced b y the anesthetic agents. Administration of 5 mg verapamil/kg im caused unexpected acute toxicity and mortality. This study suggests that pro pofol and xylazine+ketamine anesthesia in broilers may be modulated by calcium and sodium channels.