LEISHMANIA-INFANTUM NICOLLE, 1908 FROM SOUTHERN SPAIN - CHARACTERIZATION OF THE STRAINS FROM HUMAN VISCERAL AND CUTANEOUS LEISHMANIASIS ANDFROM SANDFLIES - WITH A NUMERICAL-ANALYSIS OF THE ISOENZYMATIC DATA
Jm. Sanchez et al., LEISHMANIA-INFANTUM NICOLLE, 1908 FROM SOUTHERN SPAIN - CHARACTERIZATION OF THE STRAINS FROM HUMAN VISCERAL AND CUTANEOUS LEISHMANIASIS ANDFROM SANDFLIES - WITH A NUMERICAL-ANALYSIS OF THE ISOENZYMATIC DATA, Systematic parasitology, 33(3), 1996, pp. 177-182
This study presents the results of the characterisation of 17 strains
of Leishmania by isoenzyme electrophoresis from a focus of leishmanias
is in southern Spain: two from human visceral leishmaniasis, four from
human cutaneous leishmaniasis and 11 from sandflies. The 17 strains a
re grouped in 6 zymodemes characterised by their variability as regard
s to the electrophoretic mobility of the enzymes MDH, G6PD, NP and ME.
Thus, we confirm the high intraspecific variability of Leishmania (L.
) infantum in a focus of southern Spain, as already suggested by previ
ous studies. Zymodemes GR-15 and GR-17 are also described for the firs
t time in Spain, and they characteristically possess the same relative
electrophoretic mobility in the enzyme ME (93). Sixteen zymodemes of
the L. infantum complex found in southern Spain were numerically analy
sed on the basis of the enzymatic profiles of 122 Leishmania strains c
haracterised from this area.