A 52 year old man developed an extraskeletal mesenchymal chondrosarcom
a (ESMC) arising from the pleura Clinically, the tumour mimicked a mes
othelioma. Fine needle biopsy was consistent with the diagnosis of sar
comatoid mesothelioma. Histological examination of multiple tumour sam
ples, supported by immunohistochemical characterization, made it possi
ble to correctly diagnose extraskeletal mesenchymal chondrosarcoma.