PYODERMA-GANGRENOSUM ASSOCIATED WITH CYSTIC ACNE AND HIDRADENITIS SUPPURATIVA CONTROLLED BY ADDING MINOCYCLINE AND SULFASALAZINE TO THE TREATMENT REGIMEN
Pd. Shenefelt, PYODERMA-GANGRENOSUM ASSOCIATED WITH CYSTIC ACNE AND HIDRADENITIS SUPPURATIVA CONTROLLED BY ADDING MINOCYCLINE AND SULFASALAZINE TO THE TREATMENT REGIMEN, Cutis, 57(5), 1996, pp. 315-319
Pyoderma gangrenosum often presents a difficult therapeutic challenge.
The case is described of a 42-year-old black man with the association
of cystic acne, hidradenitis suppurativa, and seronegative arthritis
with pyoderma gangrenosum. The pyoderma gangrenosum ulcers remained re
fractory to treatment until therapies aimed in part at the associated
diseases were begun. Minocycline was given for treatment of cystic acn
e and hidradenitis suppurativa as well as pyoderma gangrenosum. Sulfas
alazine was prescribed for seronegative arthritis as well as pyoderma
gangrenosum. The combination therapy permitted healing of the pyoderma
gangrenosum ulcers.