A 58-year-old man with primary large cell carcinoma of the lung presen
ted with rapidly progressive, bilateral visual loss. The patient was a
lert and oriented, had no complaints of headache, and was found to hav
e full ocular motility. The optic disks and fundi appeared normal. No
visual pathway lesions or other CNS abnormalities were detected on neu
ro-imaging. The authors discuss their differential diagnosis, clinical
diagnostic approach, and subsequent management of this unusual patien
t.