SPINAL MENINGEAL MELANOCYTOMA - CASE-REPORT AND ANALYSIS OF DIAGNOSTIC-CRITERIA

Citation
A. Ruelle et al., SPINAL MENINGEAL MELANOCYTOMA - CASE-REPORT AND ANALYSIS OF DIAGNOSTIC-CRITERIA, Neurosurgical review, 19(1), 1996, pp. 39-42
Citations number
15
Categorie Soggetti
Clinical Neurology",Surgery
Journal title
ISSN journal
03445607
Volume
19
Issue
1
Year of publication
1996
Pages
39 - 42
Database
ISI
SICI code
0344-5607(1996)19:1<39:SMM-CA>2.0.ZU;2-A
Abstract
A case of cervical juxtamedullary meningeal melanocytoma is presented along with results of careful neuroradiological and pathological exami nations. The authors review the previous literature and discuss the pr oblems related to the intriguing diagnosis of this very rare entity CT and MRI show variable appearances due to different degrees of melaniz ation and do not reliably allow us to distinguish meningeal melanocyto mas from other pigmented tumors. Pathological examination of the tumor is critical for diagnosis, but it absolutely must comprise electron m icroscopy and immunohistochemistry. Immunohistochemical and ultrastruc tural criteria are thus proposed to distinguish meningeal melanocytoma from pigmented meningioma or schwannoma and malignant melanoma (prima ry or secondary).