Among 103 neuro-Behcet's disease (NBD) patients seen in an 8-year peri
od, 16 patients with intracranial hypertension (IH) are presented, The
main underlying cause of IH was cerebral venous thrombosis (10 patien
ts), and one patient showed vena cava superior thrombosis, while in th
ree patients angiographies and/or MRI studies remained negative, In th
e remaining two patients the investigations were not adequate to exclu
de cerebral venous thrombosis, In a mean follow-up period of 5 years,
three patients had one recurrence of IH, and the three cases in whom c
erebral venous thrombosis could not be documented despite adequate inv
estigation had frequent relapses, On follow-up, none of the patients h
ad any other types of neurologic involvement, Among the other manifest
ations of Behcet's disease thrombophlebitis was significantly higher,
whereas uveitis was significantly lower in IH patients when compared w
ith our remaining NBD patients, Intracranial hypertension is one of th
e major types of neurologic involvement in Behcet's disease, and seems
to have different pathogenetic implications, usually with a better ou
tcome than other types of neurologic involvement.