We report a patient who exhibited severe tremor in the right hand and
fingers primarily while writing. Tremor showed no improvement with var
ious medications, including proplanolol and clonazepam. Writing and dr
awing difficulties of the patient gradually decreased from the third w
eek of lisuride treatment, and his tremor was totally abolished at the
end of the eighth week. When he interrupted lisuride treatment for a
few days, his tremor increased again over the next few days. He made t
he second full recovery after new treatment with lisuride. Regarding i
ts response to a dopaminergic agonist, it may be suggested that primar
y writing tremor might arise in basal ganglia or related structures in
the brain.