DNA MINOR-GROOVE ACCESSIBILITY IN THE NUCLEOSOME CORE DEDUCED FROM SPECIFIC INTERACTIONS WITH DAPI

Authors
CANEVA R ROSSETTI L SAVINO M
Citation
R. Caneva et al., DNA MINOR-GROOVE ACCESSIBILITY IN THE NUCLEOSOME CORE DEDUCED FROM SPECIFIC INTERACTIONS WITH DAPI, Biochimica et biophysica acta, N. Gene structure and expression, 1306(2-3), 1996, pp. 117-121
Citations number
25
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1306
Issue
2-3
Year of publication
1996
Pages
117 - 121
Database
ISI
SICI code
0167-4781(1996)1306:2-3<117:DMAITN>2.0.ZU;2-3
Abstract
Equilibrium binding properties of DAPI for purified nucleosome cores w ere derived from fluorescence intensity enhancement. Both the affinity and the number of sites of the primary, minor groove binding are pres erved with respect to the corresponding isolated DNA, suggesting that the capacity for specific interactions of the minor groove may well be exerted in chromatin.