Na. Lissy et al., ISOLATION, CHARACTERIZATION, AND MAPPING TO HUMAN-CHROMOSOME 11Q24-25OF A CDNA-ENCODING A HIGHLY CONSERVED PUTATIVE TRANSMEMBRANE PROTEIN,TMC, Biochimica et biophysica acta, N. Gene structure and expression, 1306(2-3), 1996, pp. 137-141
We report the isolation of a novel human cDNA encoding a putative tran
smembrane protein, TMC. The predicted protein sequence is highly conse
rved evolutionarily. The cDNA done was mapped to human chromosome 11q2
4-25 by fluorescence in situ hybridization. mRNA expression was observ
ed in all tissues tested with the highest levels in testes and ovary.