We examined eight patients with primary spinal epidural non-Hodgkin's
lymphoma presenting with spinal cord compression and proven histologic
ally after laminectomy (7 cases) or biopsy (1 case) by MRI. The most c
ommon findings were an isointense or low signal relative to the spinal
cord on T1-weighted images (T1WI) and high signal on T2-weighted imag
es (T2WI). Spinal cord compression, vertebral bone marrow and paravert
ebral extension were assessed. Contrast enhancement was intense in sev
en of the eight cases and homogeneous in all of them. T2WI (performed
in 2 cases) may be useful to distinguish metastatic carcinomas and sar
comas. T1WI demonstrated the full extent of the epidural lesion, which
was well-delineated in all cases. When the paravertebral extension is
not well defined, a study with contrast medium should be performed.